Vitamin B12, also called cobalamin, is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. It is one of the eight B vitamins. It is normally involved in the metabolism of every cell of the human body, especially affecting DNA synthesis and regulation, but also fatty acid synthesis and energy production. B12 also plays a role in cellular repair, an important role in managing Crohn's disease.
Crohn's disease can damage the ileum, the lower part of the intestine necessary for vitamin B12 absorption. Sometimes portions of the ileum have to be surgically removed. This often leads to B12 deficiencies that can manifest as weakness, fatigue, light-headedness, and megaloblastic anemia (larger-than-normal red blood cells). In extreme cases, it can damage the nerves, resulting in tingling or numbness in fingers and toes and difficulty walking. B12 solid form supplements are regularly prescribed and liquid injections are given in cases where other supplementation is inadequate.
Information from Health.com
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